Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360833 | 0.91 | RORC (0.32) | RORCBRAF | |
| SCHEMBL9360821 | 0.85 | BRD4 (0.33) | KMT2ARORCEGLN1BRAFMMP13 | |
| SCHEMBL633608 | 0.85 | BRD4 (0.34) | MEN1KMT2ATDP1EGLN1MMP13 | |
| Hydrochloric Acid SCHEMBL3136757 | 0.83 | BRD4 (0.33) | MEN1KMT2ATDP1EGLN1MMP13 | |
| SCHEMBL9359791 | 0.82 | CDK1 (0.32) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL9360081 | 0.78 | MMP13 (0.36) | MEN1KMT2ATDP1EGLN1MMP13 | |
| SCHEMBL7131959 | 0.78 | BRD4 (0.36) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL785277 | 0.76 | LMNA (0.33) | MEN1KMT2ATDP1 | |
| SCHEMBL1830339 | 0.73 | MEN1 (0.48) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL28567301 | 0.73 | CAMKK2 (0.42) | MEN1KMT2AEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434727-A4 | RED-SHIFTED PHTHALOCYANINE AND TETRABENZTRIAZAPORPHYRIN REAGENTS | ULTRA DIAGNOSTIC CORP (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0434727-A1 | RED-SHIFTED PHTHALOCYANINE AND TETRABENZTRIAZAPORPHYRIN REAGENTS | BRITISH TECHNOLOGY GROUP (USA) INCORPORATED (US) | 1991-07-03 | — | — | EP | disclosed |
| WO-1990002747-A1 | RED-SHIFTED PHTHALOCYANINE AND TETRABENZTRIAZAPORPHYRIN REAGENTS | ULTRA DIAGNOSTICS CORPORATION (US) | 1990-03-22 | — | — | WO | disclosed |