Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359937 | 0.77 | RAB9A (0.36) | ALDH1A1SMN1; SMN2MAPTRAB9AL3MBTL1 | |
| SCHEMBL822287 | 0.76 | ALDH1A1 (0.42) | NOTUMALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL2290788 | 0.76 | FBP1 (0.36) | ALDH1A1SMN1; SMN2MAPTKDM4ELMNA | |
| SCHEMBL10007491 | 0.71 | ESR1 (0.54) | NOTUMALDH1A1MAPTPOLBLMNA | |
| SCHEMBL12792105 | 0.69 | TDP1 (0.36) | NOTUMALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL12792120 | 0.68 | ACHE (0.42) | ALDH1A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL11947073 | 0.67 | ALDH1A1 (0.39) | NOTUMALDH1A1HPGD | |
| SCHEMBL20550992 | 0.67 | FBP1 (0.36) | ALDH1A1SMN1; SMN2MAPTKDM4ELMNA | |
| SCHEMBL3313456 | 0.67 | ALDH1A1 (0.42) | NOTUMALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL2341397 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292260-B1 | Process for producing 1,3-bis(dicarboxyphenyl)-disiloxane derivative or dianhydride thereof | HITACHI CHEMICAL CO LTD (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5166363-A | Process for producing 1,3-bis(dicarboxyphenyl)-disiloxane derivative or dianhydride thereof | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0292260-A2 | Process for producing 1,3-bis(dicarboxyphenyl)-disiloxane derivative or dianhydride thereof | Hitachi Chemical Co., Ltd. (JP) | 1988-11-23 | — | — | EP | disclosed |