Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CD38 | P28907 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | ADH5 | P11766 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PRKCG | P05129 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9367421 | 0.99 | CYP4Z1 (0.63) | CYP4Z1ADRB1ADRB2ADRB3ALDH1A1 | |
| SCHEMBL3043398 | 0.91 | ADRB1 (0.56) | CYP4Z1ADRB1ADRB2ADRB3ALDH1A1 | |
| SCHEMBL3030365 | 0.90 | ADRB2 (0.58) | CYP4Z1ADRB1ADRB2ADRB3DRD3 | |
| SCHEMBL8508590 | 0.87 | CYP4Z1 (0.65) | CYP4Z1ADRB1ADRB2ADRB3MAPT | |
| SCHEMBL9364539 | 0.82 | CYP4Z1 (0.59) | CYP4Z1ADRB1ADRB2ADRB3MAPT | |
| Water SCHEMBL9367478 | 0.81 | CYP4Z1 (0.58) | CYP4Z1ADRB1ADRB2ADRB3MAPT | |
| Water SCHEMBL9367484 | 0.81 | CYP4Z1 (0.58) | CYP4Z1ADRB1ADRB2ADRB3MAPT | |
| SCHEMBL5947724 | 0.80 | EPHX2 (0.64) | CYP4Z1ADRB1ADRB2ADRB3MAPT | |
| SCHEMBL16781355 | 0.79 | LMNA (0.53) | ADRB1ADRB2ADRB3MAPTADH5 | |
| SCHEMBL8781065 | 0.79 | CYP4Z1 (0.57) | CYP4Z1ADRB1ADRB2ADRB3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290377-B1 | Substituted 4-[1H-Imidazol-1-yl] benzamides as antiarrhythmic agents | SCHERING AG (DE) | 1994-03-02 | — | — | EP | claimed |
| US-4804662-A | Substituted 4-(1H-imidazol-1-yl)benzamides as antiarrhythmic agents | SCHERING A.G. (DE) | 1989-02-14 | — | — | US | claimed |
| EP-0290377-B1 | Substituted 4-[1H-Imidazol-1-yl] benzamides as antiarrhythmic agents | SCHERING AG (DE) | 1994-03-02 | — | — | EP | disclosed |
| US-4804662-A | Substituted 4-(1H-imidazol-1-yl)benzamides as antiarrhythmic agents | SCHERING A.G. (DE) | 1989-02-14 | — | — | US | disclosed |