Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010851 | 0.81 | PTGS1 (0.41) | PTGS1AKR1C3AKR1C2TDP1NR1H4 | |
| SCHEMBL11275952 | 0.78 | GAA (0.68) | PTGS1AKR1C3AKR1C2GAATSHR | |
| SCHEMBL7632086 | 0.74 | CA2 (0.56) | PTGS1KDM4ELMNAHIF1AHSD17B10 | |
| SCHEMBL24476689 | 0.71 | CTBP2 (0.51) | NFKB1KDM4ELMNAMAPTBLM | |
| SCHEMBL6349150 | 0.71 | TRPA1 (0.64) | AKR1C3AKR1C2POLBALOX5LCK | |
| SCHEMBL18904521 | 0.70 | EPHX2 (0.41) | PTGS1AKR1C3AKR1C2GAATSHR | |
| SCHEMBL10174346 | 0.70 | HPGD (0.49) | GAATDP1LMNAPOLBMAPT | |
| SCHEMBL24164778 | 0.69 | HTT (0.59) | KDM4ELMNAPOLBMAPTALDH1A1 | |
| SCHEMBL8847943 | 0.69 | NPC1 (0.55) | PTGS1KDM4ELMNAHPGDHIF1A | |
| SCHEMBL9364458 | 0.69 | PTGS1 (0.42) | PTGS1AKR1C3AKR1C2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |