Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.38 |
| ▸ | OGA | O60502 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977487 | 0.80 | RAB9A (0.49) | NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL8977464 | 0.79 | LCK (0.54) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL10926694 | 0.79 | CTSS (0.41) | KDM4ECTSSCTSKS1PR3 | |
| SCHEMBL10627562 | 0.78 | CTSS (0.43) | NPC1RAB9AKDM4ETDP1CTSS | |
| SCHEMBL10631857 | 0.77 | ALDH1A1 (0.45) | NPC1RAB9ATAS1R3TAS1R1CTSS | |
| SCHEMBL11121473 | 0.76 | CTSS (0.41) | CTSSCTSKS1PR3 | |
| SCHEMBL25382759 | 0.75 | NPC1 (0.51) | IRAK4NPC1RAB9AKDM4EHKDC1 | |
| SCHEMBL30554088 | 0.75 | NPC1 (0.51) | IRAK4NPC1RAB9AKDM4EHKDC1 | |
| SCHEMBL9619945 | 0.75 | CTSS (0.38) | NPC1RAB9ACTSSCTSKS1PR3 | |
| SCHEMBL10725965 | 0.75 | YARS1 (0.47) | KDM4ETDP1CTSSCTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292806-B1 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1994-11-02 | — | — | EP | disclosed |
| US-5171854-A | Antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-15 | — | — | US | disclosed |
| EP-0292806-A2 | Substituted vinyl cephalosporins, process for their preparation and their use as medicines | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |