Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366182 | 1.00 | RAB9A (0.54) | RAB9ALMNAL3MBTL1NAPRTP4HTM | |
| SCHEMBL6274157 | 0.82 | NPC1 (0.54) | RAB9ALMNAL3MBTL1NAPRTP4HTM | |
| SCHEMBL12658778 | 0.79 | CES2 (0.52) | RAB9ALMNAL3MBTL1NAPRTP4HTM | |
| SCHEMBL9509537 | 0.77 | TDP1 (0.47) | RAB9ALMNAL3MBTL1TDP1NPC1 | |
| SCHEMBL9507234 | 0.77 | RAB9A (0.51) | RAB9ALMNAL3MBTL1TDP1NPC1 | |
| SCHEMBL9509534 | 0.77 | TDP1 (0.47) | RAB9ALMNAL3MBTL1TDP1NPC1 | |
| SCHEMBL9507236 | 0.77 | RAB9A (0.51) | RAB9ALMNAL3MBTL1TDP1NPC1 | |
| SCHEMBL13662201 | 0.76 | NPC1 (0.59) | RAB9ALMNAL3MBTL1NAPRTP4HTM | |
| 2-Picolinic Acid SCHEMBL906806 | 0.75 | LMNA (0.71) | RAB9ALMNAL3MBTL1NAPRTP4HTM | |
| SCHEMBL10707162 | 0.75 | ALDH1A1 (0.48) | RAB9ALMNAL3MBTL1NAPRTP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441207-B1 | Heteroaryl alkenes, process for their preparation, intermediates and their use | BASF AG (DE) | 1994-03-30 | — | — | EP | disclosed |