Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9365701 | 0.88 | LMNA (0.79) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9369302 | 0.88 | LMNA (0.78) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8342494 | 0.86 | LMNA (0.75) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7340898 | 0.86 | LMNA (0.76) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8342323 | 0.84 | LMNA (0.72) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9365729 | 0.84 | LMNA (0.72) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29624123 | 0.84 | KMT2A (0.72) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9365654 | 0.83 | LMNA (0.71) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9369348 | 0.83 | LMNA (0.71) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9365369 | 0.81 | ALDH1A1 (0.68) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579695-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992016508-A1 | REISSERT COMPOUNDS AS ANTI-HIV AGENTS | THE UPJOHN COMPANY (US) | 1992-10-01 | — | — | WO | disclosed |