Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HINT1 | P49773 | 6/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | PNP | P00491 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanosine SCHEMBL3492467 | 0.96 | HPGD (0.59) | HPGDHINT1NT5EGSK3ARPS6KA3 | |
| Guanosine SCHEMBL3055871 | 0.93 | HPGD (0.63) | HPGDHINT1NT5EGSK3ARPS6KA3 | |
| Guanosine SCHEMBL29045171 | 0.92 | HPGD (0.60) | HPGDHINT1NT5EGSK3ARPS6KA3 | |
| Guanosine SCHEMBL8995759 | 0.90 | HPGD (0.62) | HPGDHINT1NT5EGSK3ARPS6KA3 | |
| Guanosine SCHEMBL27641680 | 0.89 | ADORA3 (0.49) | HPGDHINT1NT5EADORA2AADORA2B | |
| Adenosine SCHEMBL21854749 | 0.88 | ADORA3 (0.54) | ADORA2AADORA2B | |
| Guanosine SCHEMBL8199838 | 0.87 | DPP4 (0.49) | HPGDADORA2AADORA2B | |
| Adenosine SCHEMBL21854748 | 0.87 | ADORA3 (0.52) | HPGDADORA2AADORA2B | |
| Guanosine SCHEMBL9138605 | 0.85 | HPGD (0.58) | HPGDHINT1NT5EGSK3ARPS6KA3 | |
| Inosine SCHEMBL3799120 | 0.85 | PAX8 (0.49) | HPGDPAX8ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130280297-A1 | USE OF TOXOPLASMA GENE PRODUCTS TO PREVENT OR TREAT MICROBIAL INFECTIONS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-10-24 | — | — | US | disclosed |
| US-20120189581-A1 | USE OF TOXOPLASMA AND DERIVED COMPOSITIONS TO PREVENT OR TREAT MICROBIAL INFECTIONS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2012-07-26 | — | — | US | disclosed |
| WO-2011011725-A2 | USE OF TOXOPLASMA AND DERIVED COMPOSITIONS TO PREVENT OR TREAT MICROBIAL INFECTIONS | SCHULTZ-CHERRY STACEY L (US) | 2011-01-27 | — | — | WO | disclosed |