Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.34 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137556 | 0.75 | TSHR (0.42) | HSD17B10TSHRHPGDAKR1B1AKR1C2 | |
| SCHEMBL3720608 | 0.73 | WDR5 (0.41) | HSD17B10TSHRHPGDAKR1B1AKR1C2 | |
| SCHEMBL3203026 | 0.72 | AKR1C2 (0.49) | HSD17B10TSHRHPGDMAPK1AKR1C2 | |
| SCHEMBL10922213 | 0.72 | NOTUM (0.39) | HSD17B10TSHRHPGDMAPK1AKR1B1 | |
| SCHEMBL10710521 | 0.71 | EPHX2 (0.37) | PGK1SLC1A5KMONOTUMGRIN2B | |
| SCHEMBL10922521 | 0.69 | NOTUM (0.37) | PGK1NOTUMGRIN2B | |
| SCHEMBL10695590 | 0.68 | HSD17B10 (0.52) | HSD17B10TSHRHPGDMAPK1AKR1B1 | |
| SCHEMBL16071616 | 0.68 | PGK1 (0.37) | PGK1SLC1A5NOTUM | |
| SCHEMBL10708527 | 0.68 | NOTUM (0.36) | MAPK1CYP3A4PGK1SLC1A5KMO | |
| SCHEMBL8462165 | 0.68 | EPHX2 (0.41) | PGK1SLC1A5KMONOTUMPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365915-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-4956370-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| EP-0368008-A1 | Fluorine-containing phenols | BAYER AG (DE) | 1990-05-16 | — | — | EP | disclosed |
| EP-0365915-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |