Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489664 | 0.86 | AKR1C2 (0.43) | AKR1C2AKR1C1HSD17B10TTRTSHR | |
| SCHEMBL3205177 | 0.86 | AKR1C2 (0.43) | AKR1C2AKR1C1HSD17B10TTRTSHR | |
| SCHEMBL10698454 | 0.84 | HSD17B10 (0.42) | AKR1C2AKR1C1HSD17B10TTRTSHR | |
| SCHEMBL7928085 | 0.81 | ALDH1A1 (0.39) | AKR1C2AKR1C1HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL11274922 | 0.79 | GPR3 (0.36) | AKR1C2AKR1C1RECQLCYP2C9MAPK1 | |
| SCHEMBL1040929 | 0.79 | GPR3 (0.41) | AKR1C2AKR1C1RECQLCYP2C9MAPK1 | |
| SCHEMBL25372577 | 0.77 | GPR3 (0.35) | AKR1C2AKR1C1RECQLCYP2C9MAPK1 | |
| SCHEMBL9224313 | 0.77 | GPR3 (0.35) | AKR1C2AKR1C1RECQLWDR5CYP2C9 | |
| SCHEMBL12536048 | 0.77 | GPR3 (0.37) | AKR1C2AKR1C1TSHRALDH1A1CYP3A4 | |
| SCHEMBL342267 | 0.77 | ALDH1A1 (0.44) | AKR1C2AKR1C1HSD17B10ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4700006-A | FUNGICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-10-13 | — | — | US | claimed |
| JP-61194042-A | — | — | None | — | — | JP | disclosed |
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2088861-A2 | BENZIMIDAZOLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008051533-A2 | BENZIMIDAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |
| US-4700006-A | FUNGICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-10-13 | — | — | US | disclosed |
| US-4609669-A | AGRICULTURE, HORTICULTURE | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-09-02 | — | — | US | disclosed |
| JP-S61194042-A | NOVEL SUBSTITUTED PHENOL | NIPPON TOKUSHU NOYAKU SEIZO KK | 1986-08-28 | — | — | JP | disclosed |
| EP-0175188-A1 | Carbamoylimidazole derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056515-A1 | BENZIMIDAZOLE COMPOUNDS | HRH4, SSTR5, CNR1 | AKR1C2 757/4885AKR1C1 654/4885HSD17B10 1266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.