Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368918 | 0.88 | ALDH1A1 (0.47) | ALDH1A1PKMNPC1RAB9ANPSR1 | |
| SCHEMBL9363575 | 0.87 | PKM (0.51) | ALDH1A1POLBPKMGAATSHR | |
| SCHEMBL9368889 | 0.86 | ALDH1A1 (0.46) | ALDH1A1POLBPKMNPC1RAB9A | |
| SCHEMBL9363777 | 0.81 | NPC1 (0.49) | ALDH1A1PKMNPC1RAB9ANPSR1 | |
| SCHEMBL9183520 | 0.77 | ACHE (0.41) | ALDH1A1POLBPKMNPC1RAB9A | |
| SCHEMBL7975241 | 0.72 | GAA (0.50) | POLBPKMNPC1RAB9AGAA | |
| SCHEMBL11551662 | 0.71 | PKM (0.59) | ALDH1A1PKMGAATSHR | |
| SCHEMBL9367365 | 0.71 | PKM (0.59) | ALDH1A1PKMGAATSHRLMNA | |
| SCHEMBL10364285 | 0.70 | NPC1 (0.36) | ALDH1A1PKMNPC1RAB9ANPSR1 | |
| SCHEMBL10364282 | 0.70 | NPC1 (0.36) | ALDH1A1PKMNPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464112-B1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS | GEA FARMACEUTISK FABRIK AS (DK) | 1994-10-05 | — | — | EP | disclosed |
| US-5223619-A | Catalytic cyclization | A/S GEA FARMACEUTISK FABRIK (DK) | 1993-06-29 | — | — | US | disclosed |
| EP-0464112-A1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS. | GEA FARMACEUTISK FABRIK AS (DK) | 1992-01-08 | — | — | EP | disclosed |
| WO-1990011283-A1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS | A/S GEA FARMACEUTISK FABRIK (DK) | 1990-10-04 | — | — | WO | disclosed |