Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.51 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.40 |
| ▸ | OGT | O15294 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647933 | 0.79 | ALDH1A1 (0.60) | CREBBPKDM4EALDH1A1SMYD3ESR1 | |
| SCHEMBL7371232 | 0.77 | MGAM (0.76) | TOP2ATOP2BCHEK2KDM4EALDH1A1 | |
| SCHEMBL9469729 | 0.76 | TOP2A (0.51) | TOP2ATOP2BCHEK2KDM4EALDH1A1 | |
| SCHEMBL9368243 | 0.76 | ALDH1A1 (0.53) | CREBBPKDM4EALDH1A1SMYD3ESR1 | |
| Bromide SCHEMBL7374451 | 0.76 | MGAM (0.73) | TOP2ATOP2BCHEK2KDM4EALDH1A1 | |
| SCHEMBL9684957 | 0.75 | CNR2 (0.50) | CREBBPKDM4EALDH1A1SMYD3ESR1 | |
| SCHEMBL17260664 | 0.72 | KDM4E (0.62) | CREBBPKDM4EALDH1A1SMYD3NOS1 | |
| SCHEMBL31629977 | 0.72 | MGAM (0.78) | TOP2ATOP2BCHEK2KDM4EALDH1A1 | |
| SCHEMBL28286128 | 0.72 | MGAM (0.78) | TOP2ATOP2BCHEK2KDM4EALDH1A1 | |
| SCHEMBL9684816 | 0.72 | ALDH1A1 (0.55) | CREBBPKDM4EALDH1A1SMYD3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |