Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368759 | 0.93 | GABRA1 (0.39) | DUSP3PTPN11ALDH1A1SMN1; SMN2GABRA1 | |
| SCHEMBL9371953 | 0.83 | NLRP3 (0.35) | KMT2AALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL9368050 | 0.81 | NLRP3 (0.34) | KMT2AALDH1A1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL9373260 | 0.78 | ITGB1 (0.39) | ALDH1A1SMN1; SMN2GABRA1GABRG2GABRB3 | |
| SCHEMBL9369273 | 0.77 | NLRP3 (0.37) | KMT2AALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL9368867 | 0.76 | HPGD (0.40) | KMT2AALDH1A1SMN1; SMN2GAATDP1 | |
| SCHEMBL9368764 | 0.74 | NLRP3 (0.33) | KMT2AALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL9373305 | 0.73 | RORC (0.41) | KMT2AALDH1A1SMN1; SMN2LMNATDP1 | |
| SCHEMBL9368573 | 0.73 | TDP1 (0.38) | KMT2AALDH1A1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL8744754 | 0.73 | NLRP3 (0.34) | KMT2AALDH1A1SMN1; SMN2MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377893-B1 | 3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5186737-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| US-5045560-A | Insecticides, nematocides, fungicides, herbicides, human and veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0377893-A2 | 3-Aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1990-07-18 | — | — | EP | disclosed |