Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368700 | 0.84 | PTPN1 (0.47) | KMT2AL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL9369194 | 0.82 | NPC1 (0.49) | KMT2A | |
| SCHEMBL9538478 | 0.82 | PTGES (0.53) | KMT2A | |
| SCHEMBL9368612 | 0.81 | PTGES (0.52) | KMT2ASMN1; SMN2 | |
| SCHEMBL1790172 | 0.80 | MAPT (0.50) | KMT2AL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL1789016 | 0.79 | MAPT (0.51) | KMT2AL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL9368458 | 0.79 | PTGES (0.45) | KMT2AMAPTTDP1 | |
| SCHEMBL9538619 | 0.78 | NR3C1 (0.46) | KMT2AL3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL17236371 | 0.78 | KMT2A (0.55) | KMT2AL3MBTL1MAPTTDP1ALDH1A1 | |
| SCHEMBL9538851 | 0.77 | FFAR1 (0.48) | MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |