Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538619 | 0.91 | NR3C1 (0.46) | PTPN1CETPCRHBPCRHR2MAPT | |
| SCHEMBL9369224 | 0.84 | ACACB (0.46) | MAPTTDP1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL9373488 | 0.84 | PTPN1 (0.51) | PTPN1CRHBPCRHR2ALOX5KMT2A | |
| SCHEMBL9541480 | 0.83 | RAB9A (0.45) | PTPN1CRHBPCRHR2MAPTTDP1 | |
| SCHEMBL9368458 | 0.83 | PTGES (0.45) | MAPTTDP1ALOX5KMT2A | |
| SCHEMBL1789016 | 0.81 | MAPT (0.51) | MAPTTDP1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL9368612 | 0.80 | PTGES (0.52) | CETPALOX5KMT2A | |
| SCHEMBL9369194 | 0.80 | NPC1 (0.49) | CETPALOX5KMT2A | |
| SCHEMBL1790172 | 0.79 | MAPT (0.50) | MAPTTDP1ALOX5KMT2AL3MBTL1 | |
| SCHEMBL17236371 | 0.79 | KMT2A (0.55) | MAPTTDP1ALOX5KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |