Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463624 | 0.85 | CA5A (0.49) | OPRK1KDM1AALDH1A1ROCK2PIM1 | |
| SCHEMBL16401680 | 0.72 | HDAC1 (0.51) | HDAC1KDM1AALDH1A1MAPTPKM | |
| SCHEMBL28794120 | 0.70 | HDAC1 (0.58) | HDAC1KDM1AALDH1A1MAPTPKM | |
| SCHEMBL10434376 | 0.69 | ALDH1A1 (0.47) | HDAC1KDM1AALDH1A1MAPTPKM | |
| SCHEMBL29113895 | 0.69 | ALDH1A1 (0.47) | HDAC1KDM1AALDH1A1MAPTPKM | |
| SCHEMBL9369986 | 0.68 | GRM2 (0.53) | ALDH1A1PKM | |
| SCHEMBL9858144 | 0.68 | CA5A (0.55) | HDAC1KDM1AALDH1A1MAPTPKM | |
| SCHEMBL5001602 | 0.67 | DRD2 (0.68) | OPRK1ALDH1A1SIGMAR1 | |
| SCHEMBL9857405 | 0.67 | CA5A (0.72) | HDAC1KDM1AALDH1A1MAPTPKM | |
| SCHEMBL30645406 | 0.67 | CA5A (0.72) | HDAC1KDM1AALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399653-B1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | WELLCOME FOUND (GB) | 1994-10-19 | — | — | EP | disclosed |
| EP-0399653-A1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |