Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.36 |
| ▸ | GLA | P06280 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | CASP1 | P29466 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376497 | 0.87 | PPIB (0.44) | ALDH1A1KDM4EGAAHPGDSMN1; SMN2 | |
| SCHEMBL9372182 | 0.84 | KMT2A (0.36) | ALDH1A1HPGDMAPTHSD17B10KMT2A | |
| SCHEMBL9371485 | 0.81 | S100A4 (0.37) | ALDH1A1KDM4ENPC1RAB9AKMT2A | |
| SCHEMBL9372114 | 0.81 | ALOX5 (0.40) | ALDH1A1SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL10435504 | 0.81 | KDM4E (0.36) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL9375674 | 0.81 | F10 (0.39) | ALDH1A1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9372466 | 0.80 | HSD11B1 (0.33) | ALDH1A1KDM4EHPGDMAPTMAOB | |
| SCHEMBL9372171 | 0.80 | F10 (0.35) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL9376016 | 0.80 | HRH4 (0.34) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9372070 | 0.80 | BACE1 (0.33) | MAPTRAB9AKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371312-B1 | Benzoxazine derivatives | MERCK PATENT GMBH (DE) | 1994-07-20 | — | — | EP | disclosed |