Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760699 | 0.80 | ALDH1A1 (0.50) | KDM4EGAAGRM5ALDH1A1MAPT | |
| SCHEMBL11206551 | 0.77 | CRHR1 (0.49) | KDM4EGAACRHR1HTR2AHTR2C | |
| SCHEMBL28477745 | 0.75 | ALDH1A1 (0.38) | HTR2AHTR2CHTR2BALDH1A1SRD5A1 | |
| SCHEMBL30678350 | 0.75 | ALDH1A1 (0.38) | HTR2AHTR2CHTR2BALDH1A1SRD5A1 | |
| SCHEMBL10493799 | 0.74 | P2RX7 (0.47) | KDM4EGAAALDH1A1MAPTLMNA | |
| SCHEMBL11144623 | 0.73 | HDAC2 (0.42) | KDM4EGAAGABRA1GABRG2GABRB3 | |
| SCHEMBL9482548 | 0.72 | KDM4E (0.42) | KDM4EGAAGABRA1GABRG2GABRB3 | |
| SCHEMBL14746122 | 0.71 | NOTUM (0.42) | KDM4EGAAALDH1A1MAPTSRD5A1 | |
| SCHEMBL4597640 | 0.70 | ALDH1A1 (0.64) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1725665 | 0.69 | ALDH1A1 (0.43) | KDM4EGAAGRM5ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315115-B1 | 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives, process for producing them and use thereof | MOCHIDA PHARM CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-4968680-A | HYPOTENSIVE, ANTIEDEMIC, DIURETIC | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0315115-A2 | 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives, process for producing them and use thereof | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-10 | — | — | EP | disclosed |