Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.49 |
| ▸ | HTR2A | P28223 | 7/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369082 | 0.90 | DRD2 (0.49) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL9375302 | 0.89 | HTR2A (0.46) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL9375348 | 0.89 | DRD2 (0.56) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL9377061 | 0.87 | HTR2A (0.44) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL9375582 | 0.85 | HTR1A (0.58) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL9370355 | 0.84 | LMNA (0.47) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL9369094 | 0.83 | HTR1A (0.59) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL9371919 | 0.83 | DRD2 (0.58) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL9369887 | 0.80 | DRD2 (0.45) | DRD2HTR2AHTR1A | |
| SCHEMBL9370385 | 0.79 | DRD2 (0.53) | DRD2HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376633-B1 | Benzoxazepine derivatives | SUNTORY LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| EP-0376633-A2 | Benzoxazepine derivatives | SUNTORY LIMITED (JP) | 1990-07-04 | — | — | EP | disclosed |