Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9377218 | 0.90 | POLB (0.50) | LMNAL3MBTL1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9369796 | 0.89 | HTR1A (0.49) | L3MBTL1CYP1A2CYP2C9HTR2AHTR1A | |
| SCHEMBL9375302 | 0.88 | HTR2A (0.46) | HTR2AHTR1ADRD2DRD4HTR2C | |
| SCHEMBL9377061 | 0.86 | HTR2A (0.44) | HTR2AHTR1ADRD2DRD4HTR2C | |
| SCHEMBL9373402 | 0.84 | DRD2 (0.49) | HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL9375582 | 0.84 | HTR1A (0.58) | HTR2AHTR1ADRD2DRD4HTR7 | |
| SCHEMBL9369481 | 0.83 | L3MBTL1 (0.47) | LMNAMAPTHTTL3MBTL1CYP1A2 | |
| SCHEMBL9369094 | 0.83 | HTR1A (0.59) | HTR2AHTR1ADRD2DRD4HTR2C | |
| SCHEMBL9369887 | 0.80 | DRD2 (0.45) | HTR2AHTR1ADRD2MCHR1 | |
| SCHEMBL9370385 | 0.78 | DRD2 (0.53) | HTR2AHTR1ADRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376633-B1 | Benzoxazepine derivatives | SUNTORY LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| EP-0376633-A2 | Benzoxazepine derivatives | SUNTORY LIMITED (JP) | 1990-07-04 | — | — | EP | disclosed |