Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374022 | 0.84 | ALOX5 (0.44) | ALDH1A1LMNACES2CES1ALOX5 | |
| SCHEMBL9374398 | 0.73 | L3MBTL1 (0.37) | CES2CES1ALOX5GSK3B | |
| SCHEMBL9373356 | 0.71 | ALOX5 (0.50) | ALDH1A1ALOX5 | |
| SCHEMBL553196 | 0.71 | TAAR1 (0.45) | SLC6A4SLC6A3 | |
| SCHEMBL4090534 | 0.71 | LMNA (0.46) | ALDH1A1LMNACES2CES1GSK3B | |
| SCHEMBL20604279 | 0.69 | LTB4R (0.43) | ALDH1A1LMNACES2CES1GSK3B | |
| SCHEMBL70199 | 0.68 | — | — | |
| SCHEMBL2037745 | 0.68 | — | — | |
| SCHEMBL436458 | 0.67 | CYP2A6 (0.51) | LMNAALOX5 | |
| SCHEMBL1400850 | 0.66 | ALDH1A1 (0.41) | ALDH1A1LMNACES2CES1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588785-A1 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1994-03-30 | — | — | EP | disclosed |
| EP-0588785-A4 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS. | ABBOTT LAB (US) | 1991-12-30 | — | — | EP | disclosed |
| WO-1990012008-A1 | UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-10-18 | — | — | WO | disclosed |