Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374266 | 0.99 | TSHR (0.43) | TSHRHTTPOLBTP53PLK1 | |
| SCHEMBL9375283 | 0.96 | TSHR (0.45) | TSHRHTTPOLBTP53PLK1 | |
| SCHEMBL9372268 | 0.85 | KMO (0.45) | TSHRHTTPOLBMAPTTERT | |
| SCHEMBL9369680 | 0.84 | L3MBTL1 (0.43) | TP53MAPTMEN1KMT2A | |
| SCHEMBL1764373 | 0.82 | TSHR (0.62) | TSHRHTTPOLBTP53PLK1 | |
| SCHEMBL9024015 | 0.81 | HTR1A (0.42) | TSHRMAPTKMT2A | |
| SCHEMBL9025337 | 0.80 | TDP1 (0.42) | — | |
| SCHEMBL7467871 | 0.80 | CHRM2 (0.40) | HTTPOLBMAPTCHRM2MEN1 | |
| SCHEMBL9371971 | 0.79 | HTR1A (0.58) | — | |
| SCHEMBL9371995 | 0.78 | HTR1A (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376633-B1 | Benzoxazepine derivatives | SUNTORY LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5071845-A | Psychotropic or anxyiolytic agent | SUNTORY LIMITED (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0376633-A2 | Benzoxazepine derivatives | SUNTORY LIMITED (JP) | 1990-07-04 | — | — | EP | disclosed |