SCHEMBL9375969

SCHEMBL9375969

Cc1cc(O)c(C(C)(C)C)cc1Sc1cc(C(C)(C)C)c(OP(O)Oc2ccccc2)cc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 4/20 0.56
TP53 P04637 3/20 0.56
ALDH1A1 P00352 3/20 0.56
CYP3A4 P08684 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
TSHR P16473 1/20 0.56
MAPK1 P28482 1/20 0.56
HIF1A Q16665 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
ESRRA P11474 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
MAPT P10636 1/20 0.32
ATP2A2 P16615 1/20 0.32
ATP2A3 Q93084 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9669859 0.89 ALOX15 (0.57) ALOX15TP53ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL10888554 0.87 ALOX15 (0.63) ALOX15TP53ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL22721253 0.84 ALOX15 (0.36) ALOX15TP53ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL9008249 0.82 ALOX15 (0.69) ALOX15TP53ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL29990451 0.81 ALOX15 (0.71) ALOX15TP53ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL1851191 0.81 ALOX15 (0.71) ALOX15TP53ALDH1A1CYP3A4SMN1; SMN2
Phenol SCHEMBL1679670 0.77 ALDH1A1 (0.77) ALOX15TP53ALDH1A1CYP3A4SMN1; SMN2
Phenol SCHEMBL6534026 0.77 ALDH1A1 (0.77) ALOX15TP53ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL9668266 0.76 ALOX15 (0.89) ALOX15TP53ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL3663625 0.76 ALOX15 (0.89) ALOX15TP53ALDH1A1CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0313676-B1 Bis-(2,2,6,6-tetramethyl-piperidyl) diimides as light stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO LTD (JP) 1994-01-26 EP disclosed
EP-0209126-B1 HYDROCARBYL(POLYPHENOL)-POLY(2,2,6,6-TETRAMETHYL PIPERIDYL-1,3,5-TRIAZINES) AS STABILIZERS FOR SYNTHETIC POLYMER COMPOSITIONS ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1992-01-02 EP disclosed
US-4910238-A Photostable polyvinyl chloride ADEKA ARGUS CHEMICAL CO. LTD. (JP) 1990-03-20 US disclosed
US-4871793-A Polyphenylene sulfide resin compositions having improved resistance to deterioration when exposed to light and containing alkylidene bis (benzotriazolylphenols) NAKAHARA YUTAKA (JP) 1989-10-03 US disclosed
US-4822522-A LIGHT RESISTANT AGENTS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1989-04-18 US disclosed
US-4812498-A Polycarbonate resin compositions having improved resistance to deterioration when exposed to light and containing alkylidene bis(benzotriazolyl phenols) ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1989-03-14 US disclosed
US-4798836-A Bis-(2,2,6,6-tetramethyl-piperidyl) diimides as light stabilizers for synthetic polymers ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1989-01-17 US disclosed
US-4782170-A Liquid polyvinyl chloride resin stabilizer systems based on complexes of organic triphosphites with zinc chloride ARGUS CHEMICAL CORPORATION (US) 1988-11-01 US disclosed
EP-0148962-B1 BIS(2,2,6,6-TETRAMETHYLPIPERIDYL-1,3,5-TRIAZINYL)-SPIRODIAMINES AND SPIROGLYCOL ETHERS AND SYNTHETIC RESIN COMPOSITIONS CONTAINING THE SAME ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1988-10-12 EP disclosed
US-4767834-A Vinyl benzyl 2,2,6,6-tetramethyl piperidines ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1988-08-30 US disclosed
EP-0095571-A2 Polyhydric alcohol ethers of 2,2,6,6-tetramethyl-4-piperidone ketals and synthetic resin compositions ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1983-12-07 EP disclosed
US-4415689-A PHOTOSTABILIZERS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-11-15 US disclosed
US-4415688-A PHOTOSTABILIZERS; AGING RESISTANCE; FLEXIBILITY ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-11-15 US disclosed
US-4405737-A OLEFIN STABILIZERS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-09-20 US disclosed
US-4396735-A N-HETEROCYCLIC COMPOUND AND A HETEROCYCLIC ACID HYDRAZIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1983-08-02 US disclosed
US-4371651-A PHOTOSTABILITY, HEAT RESISTANCE PHOENIX CHEMICAL CORPORATION (US) 1983-02-01 US disclosed
US-4362831-A A HINDERED AND HETEROCYCLIC AMINE WITH A THIOALKANOIC ACID AMIDE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-12-07 US disclosed
EP-0046161-A2 Stabilized Polyvinylhalide resin PHOENIX CHEMICAL CORPORATION (US) 1982-02-24 EP disclosed
US-4269731-A DISCOLORATION INHIBITION; MOLDING MATERIALS ARGUS CHEMICAL CORPORATION (US) 1981-05-26 US disclosed
US-4219463-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, β-thioalkyl propionic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-08-26 US disclosed