Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27745139 | 0.98 | MAOA (0.55) | PBRM1MAOAMAOBMAPTL3MBTL1 | |
| SCHEMBL29204353 | 0.89 | PBRM1 (0.59) | PBRM1MAOAMAOBMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27745140 | 0.88 | PBRM1 (0.58) | PBRM1MAOAMAOBMAPTL3MBTL1 | |
| SCHEMBL11633589 | 0.87 | MAPT (0.60) | MAPTL3MBTL1SRD5A2PLAURAB9A | |
| SCHEMBL20491314 | 0.85 | RAB9A (0.45) | MAOAMAOBMAPTL3MBTL1SRD5A2 | |
| SCHEMBL6424653 | 0.82 | MAPT (0.52) | MAOAMAOBMAPTL3MBTL1SRD5A2 | |
| SCHEMBL27625881 | 0.82 | LOXL2 (0.51) | MAPTL3MBTL1SRD5A2PLAUSTS | |
| SCHEMBL13381372 | 0.81 | SRD5A2 (0.62) | MAPTL3MBTL1SRD5A2RAB9AKMT2A | |
| SCHEMBL7475229 | 0.81 | AKR1B1 (0.59) | MAPTL3MBTL1SRD5A2PLAURAB9A | |
| SCHEMBL166538 | 0.81 | AKR1B1 (0.58) | PBRM1MAOAMAOBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1227555-A | Cytokine production inhibitors triazepine compounds, and intermediates thereof | JAPAN TOBACCO INC (JP) | 1999-09-01 | — | — | CN | disclosed |
| CN-1171788-A | Therapeutic agent for osteoporosis and triaza * compound | JAPAN TOBACCO INC (JP) | 1998-01-28 | — | — | CN | disclosed |
| EP-0628047-A1 | NOVEL THERAPEUTICAL USE OF PYRIDYLPYRROLOTHIAZOLE CARBOXAMIDE DERIVATIVES | Aventis Pharma S.A. (FR) | 1994-12-14 | — | — | EP | disclosed |
| WO-1993017027-A1 | NOVEL THERAPEUTICAL USE OF PYRIDYLPYRROLOTHIAZOLE CARBOXAMIDE DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1993-09-02 | — | — | WO | disclosed |