Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 9/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378088 | 0.90 | HTR1A (0.34) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL9380281 | 0.77 | HTR1A (0.40) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL9523662 | 0.75 | HTR1A (0.37) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9377673 | 0.70 | HTR1A (0.36) | HTR1AADRA1DADRA1AADRA1BPABPC1 | |
| SCHEMBL1768148 | 0.70 | HTR1A (0.34) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL20746489 | 0.70 | CA2 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6245418 | 0.70 | CA2 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL20746467 | 0.70 | CA2 (0.44) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2489261 | 0.70 | HTR1A (0.34) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL13661568 | 0.69 | GAA (0.61) | HTR1AADRA1DADRA1AADRA1BPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562042-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5137892-A | Bactericides | ABBOTT LABORATORIES (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992010191-A1 | QUINOLINE, NAPHTHYRIDINE AND PYRIDOBENZOXAZINE DERIVATIVES | ABBOTT LABORATORIES (US) | 1992-06-25 | — | — | WO | disclosed |