Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.61 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.54 |
| ▸ | ABAT | P80404 | 1/20 | 0.54 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403345 | 0.83 | ALDH3A1 (0.69) | ALDH3A1ALDH5A1ABATVCAM1MAPT | |
| SCHEMBL7142928 | 0.83 | ALDH3A1 (0.69) | ALDH3A1ALDH5A1ABATVCAM1MAPT | |
| SCHEMBL2561640 | 0.78 | ALDH3A1 (0.59) | ALDH3A1ALDH5A1ABATVCAM1MAPT | |
| SCHEMBL18110635 | 0.78 | ALDH3A1 (0.62) | ALDH3A1ALDH5A1ABATVCAM1MAPT | |
| SCHEMBL6519620 | 0.78 | HCAR3 (0.47) | MAPTALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL11532383 | 0.77 | HCAR3 (0.46) | MAPTALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL12894175 | 0.77 | ALDH1A1 (0.46) | ALDH3A1MAPTALDH1A1SMN1; SMN2HCAR3 | |
| SCHEMBL9396448 | 0.77 | POLB (0.55) | MAPTALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL2559147 | 0.76 | ALDH3A1 (0.56) | ALDH3A1ALDH5A1ABATVCAM1MAPT | |
| SCHEMBL7427649 | 0.75 | CRHBP (0.50) | MAPTALDH1A1SMN1; SMN2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356234-B1 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-5047411-A | Antiulcer Agents, H2-Receptor Antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0356234-A2 | New Benzazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |