SCHEMBL6519620

SCHEMBL6519620

CC(=O)N(C)c1ccc(Oc2ccc(N(C)C(C)=O)c([N+](=O)[O-])c2)cc1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 4/20 0.47
POLB P06746 2/20 0.44
MCOLN3 Q8TDD5 1/20 0.44
ALDH1A1 P00352 5/20 0.41
HTT P42858 2/20 0.41
TSPO P30536 1/20 0.41
FSCN1 Q16658 1/20 0.41
KDM4E B2RXH2 4/20 0.40
LMNA P02545 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 3/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9396448 0.90 POLB (0.55) HCAR3POLBMCOLN3ALDH1A1KDM4E
SCHEMBL9380346 0.78 ALDH3A1 (0.61) HCAR3POLBALDH1A1KDM4ELMNA
SCHEMBL9396479 0.78 POLB (0.46) POLBMCOLN3ALDH1A1KDM4ELMNA
SCHEMBL12894175 0.78 ALDH1A1 (0.46) HCAR3POLBALDH1A1HTTFSCN1
SCHEMBL11532383 0.78 HCAR3 (0.46) HCAR3ALDH1A1HTTFSCN1KDM4E
SCHEMBL3486822 0.77 SOS1 (0.42) HCAR3POLBMCOLN3ALDH1A1HTT
SCHEMBL3487172 0.77 HCAR3 (0.40) HCAR3POLBMCOLN3ALDH1A1LMNA
SCHEMBL7427649 0.77 CRHBP (0.50) HCAR3POLBALDH1A1HTTKDM4E
SCHEMBL6671803 0.76 TSPO (0.46) HCAR3POLBALDH1A1TSPOMEN1
SCHEMBL9395762 0.74 ALDH1A1 (0.47) HCAR3POLBALDH1A1HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179028-B1 SOLVENT RESISTANT PHOTOSENSITIVE COMPOSITIONS SYNTRIX BIOCHIP INC (US) 2005-03-02 EP disclosed
US-6569598-B2 Photoresist films comprising aromatic polyamides that are stable and impervious to solvents used as barrier layers for preferential solid-phase synthesis with micron-scale resolution SYNTRIX BIOCHIP, INC. 2003-05-27 US disclosed
US-20030064316-A1 Solvent resistant photosensitive compositions US ARMY, SECRETARY OF THE ARMY 2003-04-03 US disclosed
EP-1179028-A1 SOLVENT RESISTANT PHOTOSENSITIVE COMPOSITIONS Syntrix Biochip, Inc. (US) 2002-02-13 EP disclosed
WO-2000032678-A1 SOLVENT RESISTANT PHOTOSENSITIVE COMPOSITIONS SYNTRIX BIOCHIP, INC. (US) 2000-06-08 WO disclosed