Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29449508 | 1.00 | TRPA1 (0.40) | TRPA1CA9ATMCA3CA6 | |
| SCHEMBL68013 | 0.82 | TRPA1 (0.53) | TRPA1ATMESR1ESR2TP53 | |
| SCHEMBL29620265 | 0.82 | ACHE (0.42) | CA9CA3CA6CA5ACA14 | |
| SCHEMBL29457565 | 0.82 | TRPA1 (0.53) | TRPA1ATMESR1ESR2TP53 | |
| SCHEMBL384037 | 0.82 | ACHE (0.42) | CA9CA3CA6CA5ACA14 | |
| SCHEMBL2756173 | 0.81 | CA3 (0.39) | TRPA1CA9ATMCA3CA6 | |
| SCHEMBL12582798 | 0.81 | TRPA1 (0.39) | TRPA1CA9ATMCA3CA6 | |
| SCHEMBL5669068 | 0.81 | MEN1 (0.40) | TRPA1CA9ATMCA3CA6 | |
| SCHEMBL22133743 | 0.81 | CA6 (0.39) | TRPA1CA9CA3CA6CA5A | |
| SCHEMBL9380980 | 0.79 | ALDH1A1 (0.39) | TRPA1CA9CA3CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110776441-B | Synthesis method of 4-fluoro-2, 3-dimethylphenylmethylsulfonate | 西安淳甄新材料有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-108069831-B | Method for synthesizing 2, 3-dimethyl-4-fluorophenol | 上海恩氟佳科技有限公司 | 2020-11-24 | — | — | CN | claimed |
| CN-110776441-A | Synthesis method of 4-fluoro-2, 3-dimethylphenylmethylsulfonate | 西安淳甄新材料有限公司 | 2020-02-11 | — | — | CN | claimed |
| CN-108069831-A | A kind of method for synthesizing 2,3- dimethyl -4- fluorophenols | 上海恩氟佳科技有限公司 | 2018-05-25 | — | — | CN | claimed |
| US-12030880-B2 | Iminosulfanone compound as bromodomain protein inhibitor and pharmaceutical composition and medical use thereof | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-07-09 | — | — | US | disclosed |
| US-20230227472-A1 | FUSED PYRIDONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI JEMINCARE PHARMACEUTICALS CO., LTD (CN) | 2023-07-20 | — | — | US | disclosed |
| CN-114702411-A | Method for producing 1, 2-benzenedimethanol compound | 高文作物保护公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-108602765-B | Method for producing 1, 2-benzenedimethanol compound | 高文有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-110776441-B | Synthesis method of 4-fluoro-2, 3-dimethylphenylmethylsulfonate | 西安淳甄新材料有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-110776441-B | Synthesis method of 4-fluoro-2, 3-dimethylphenylmethylsulfonate | 西安淳甄新材料有限公司 | 2022-03-22 | — | — | CN | disclosed |
| US-11274076-B2 | Process for preparing 1, 2-benzenedimethanol compound | GOWAN COMPANY, L.L.C. (US) | 2022-03-15 | — | — | US | disclosed |
| EP-3415496-B1 | PROCESS FOR PREPARING 1,2-BENZENEDIMETHANOL COMPOUND | GOWAN COMPANY L L C (US) | 2021-07-21 | — | — | EP | disclosed |
| CN-110776441-A | Synthesis method of 4-fluoro-2, 3-dimethylphenylmethylsulfonate | 西安淳甄新材料有限公司 | 2020-02-11 | — | — | CN | disclosed |
| CN-110776441-A | Synthesis method of 4-fluoro-2, 3-dimethylphenylmethylsulfonate | 西安淳甄新材料有限公司 | 2020-02-11 | — | — | CN | disclosed |
| EP-3415496-A1 | METHOD FOR PRODUCING 1, 2-BENZENE DIMETHANOL COMPOUND | SDS Biotech K. K. (JP) | 2018-12-19 | — | — | EP | disclosed |
| CN-108602765-A | Method for producing 1, 2-benzenedimethanol compound | SDS生物技术株式会社 | 2018-09-28 | — | — | CN | disclosed |
| CN-108069831-A | A kind of method for synthesizing 2,3- dimethyl -4- fluorophenols | 上海恩氟佳科技有限公司 | 2018-05-25 | — | — | CN | disclosed |
| CN-108069831-A | A kind of method for synthesizing 2,3- dimethyl -4- fluorophenols | 上海恩氟佳科技有限公司 | 2018-05-25 | — | — | CN | disclosed |
| WO-2018044136-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING DISEASES ASSOCIATED WITH POLY(ADP-RIBOSE) POLYMERASE-1 (PARP-1) | 충남대학교 산학협력단 | 2018-03-08 | — | — | WO | disclosed |
| CN-102762532-B | The manufacture method of cyano group alkenyl cyclopropanecarboxylic acid salt | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-07-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030880-B2 | Iminosulfanone compound as bromodomain protein inhibitor and pharmaceutical composition and medical use thereof | BRD4, BRD1, BRD3 | TRPA1 3975/4885CA9 4114/4885ATM 789/4885 |
| US-20230227472-A1 | FUSED PYRIDONE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | KRAS, NRAS, WEE1 | TRPA1 2960/4885CA9 3697/4885ATM 3337/4885 |
| US-11274076-B2 | Process for preparing 1, 2-benzenedimethanol compound | ADH1A, ADH1C, CYP2E1 | TRPA1 970/4885CA9 332/4885ATM 2171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.