Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 5/20 | 0.62 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639402 | 0.83 | CASP3 (0.60) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL10921721 | 0.83 | CASP3 (0.62) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL2963555 | 0.80 | CASP3 (0.68) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL11278746 | 0.80 | CASP3 (0.74) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL17948304 | 0.80 | CASP3 (0.72) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL24836229 | 0.77 | FAAH (0.76) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL3143600 | 0.77 | CASP3 (1.00) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL16071405 | 0.77 | CASP3 (0.68) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL24836231 | 0.77 | FAAH (0.81) | CASP3FAAHMGLLKAT2AKAT2B | |
| SCHEMBL29678965 | 0.77 | CASP3 (1.00) | CASP3FAAHMGLLKAT2AKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220380383-A1 | NEUROPROTECTIVE PDI MODULATING SMALL MOLECULES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-12-01 | — | — | US | disclosed |
| CN-109942505-B | Isothiazolinone compounds and corresponding use | 华东理工大学 | 2021-08-27 | — | — | CN | disclosed |
| WO-2020113222-A1 | NEUROPROTECTIVE PDI MODULATING SMALL MOLECULES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-06-04 | — | — | WO | disclosed |
| US-20160311973-A1 | CLICKABLE WATERBORNE POLYMERS AND CLICK-CROSSLINKED WATERBORNE POLYMERS, CLICKABLE FUNCTIONAL COMPOUNDS, CLICK FUNCTIONALIZED WATERBORNE POLYMERS, AND USES THEREOF | THE PENN STATE RESEARCH FOUNDATION | 2016-10-27 | — | — | US | disclosed |
| EP-0320992-B1 | Triazolodiazepine derivatives | HOFFMANN LA ROCHE (CH) | 1994-07-27 | — | — | EP | disclosed |
| EP-0320992-A2 | Triazolodiazepine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380383-A1 | NEUROPROTECTIVE PDI MODULATING SMALL MOLECULES AND METHODS OF USE THEREOF | NLN, PDIA5, PRNP | CASP3 781/4885FAAH 1657/4885MGLL 2410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.