Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MGAM | O43451 | 3/20 | 0.40 |
| ▸ | SI | P14410 | 3/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9338940 | 0.85 | MAPT (0.42) | HSD17B10MEN1MAPTKMT2ANPC1 | |
| SCHEMBL9335421 | 0.80 | ALDH1A1 (0.40) | HSD17B10ALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL9337065 | 0.78 | PFKFB3 (0.47) | MEN1ALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL9335423 | 0.76 | PRSS1 (0.38) | HSD17B10MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9339063 | 0.76 | CYSLTR1 (0.36) | HSD17B10MAPTNPC1RAB9ATRPV1 | |
| SCHEMBL9339080 | 0.73 | XDH (0.51) | HSD17B10MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9387728 | 0.71 | HSD17B10 (0.43) | HSD17B10MEN1MAPTKMT2ANPC1 | |
| SCHEMBL9383649 | 0.71 | KAT8 (0.50) | HSD17B10MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9337205 | 0.71 | KAT8 (0.50) | HSD17B10MEN1ALDH1A1MAPTHPGD | |
| SCHEMBL28258783 | 0.70 | PPARA (0.54) | HSD17B10MEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |