Sulfadimethoxine

Sulfadimethoxine

SCHEMBL93845

COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

folP

The experimentally established mechanism targets of Sulfadimethoxine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
ALDH1A1 P00352 2/20 1.00
HTR6 P50406 2/20 1.00
CYP3A4 P08684 1/20 1.00
KMT2A Q03164 4/20 0.68
AKT1 P31749 4/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
HTT P42858 1/20 0.68
CYP2C19 P33261 2/20 0.66
POLB P06746 3/20 0.60
NPSR1 Q6W5P4 1/20 0.57
ALOX12 P18054 1/20 0.57
P2RY1 P47900 1/20 0.57
GFER P55789 1/20 0.56
PDE4A P27815 1/20 0.56
AGO2 Q9UKV8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfadimethoxine SCHEMBL29363944 1.00 LMNA (1.00) LMNAALDH1A1HTR6CYP3A4KMT2A
Sulfadimethoxine SCHEMBL2430279 0.99 LMNA (0.97) LMNAALDH1A1HTR6CYP3A4KMT2A
Sulfadimethoxine SCHEMBL9486265 0.95 ALDH1A1 (0.90) LMNAALDH1A1HTR6CYP3A4KMT2A
Sulfadimethoxine SCHEMBL17102809 0.90 LMNA (0.80) LMNAALDH1A1HTR6CYP3A4KMT2A
Sulfadimethoxine SCHEMBL6006340 0.90 ALDH1A1 (0.80) LMNAALDH1A1HTR6CYP3A4KMT2A
Sulfadimethoxine SCHEMBL23928724 0.90 ALDH1A1 (0.80) LMNAALDH1A1HTR6CYP3A4KMT2A
Sulfadimethoxine SCHEMBL28086139 0.88 ALDH1A1 (0.77) LMNAALDH1A1HTR6CYP3A4KMT2A
SCHEMBL7824834 0.88 ALDH1A1 (0.78) LMNAALDH1A1HTR6CYP3A4KMT2A
SCHEMBL7837632 0.88 HTR6 (0.78) LMNAALDH1A1HTR6CYP3A4KMT2A
Sulfadimethoxine SCHEMBL13372563 0.87 ALDH1A1 (0.76) LMNAALDH1A1HTR6CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8269 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
US-20260027140-A1 COMPOSITIONS AND METHODS FOR TREATING AND AMELIORATING RESPIRATORY CONDITIONS AND INFLAMMATION OF MUCOSA ATOPIC MEDICAL INC (US) 2026-01-29 US claimed
US-12516365-B2 Biocide compositions compatible with enzyme biosensors and methods of use thereof INSTRUMENTATION LABORATORY COMPANY (US) 2026-01-06 US claimed
US-12465623-B2 Use of parasites and extracellular vesicles obtained from parasites in cancer treatment YEDITEPE UNIVERSITESI (TR) 2025-11-11 US claimed
EP-4637829-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF OVARIAN CANCER Cellis Sp. z o.o. ([Ltd.] (PL) 2025-10-29 EP claimed
EP-4630446-A1 ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
EP-4630043-A1 IMMUNE-ACTIVATING COMPLEXES Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
US-20250314664-A1 COMPOSITIONS AND METHODS TO DETECT INFECTIOUS ORGANISMS MARS, INCORPORATED (US) 2025-10-09 US claimed
EP-3965808-B1 USE OF PARASITES AND EXTRACELLULAR VESICLES OBTAINED FROM PARASITES IN CANCER TREATMENT UNIV YEDITEPE (TR) 2025-09-03 EP claimed
EP-4594520-A2 COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS Sixfold Bioscience Ltd. (GB) 2025-08-06 EP claimed
US-4332796-A MICROCRYSTALS COATED WITH MIXTURES OF PHOSPHOLIPIDS AND NONIONIC SURFACTANTS LABORATORIOS BAGO S.A. (AR) 1982-06-01 US claimed
US-4315931-A MICROBIOCIDES, INFECTIOUS DISEASES BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US claimed
US-4277248-A FORMATION OF SCHIFF BASE WITH P-DIMETHYLAMINOCINNAMALDEHYDE HOFFMANN-LA ROCHE INC. (US) 1981-07-07 US claimed
EP-0021847-A2 Long acting sulfonamide injectable compositions PFIZER INC. (US) 1981-01-07 EP claimed
US-4169763-A OF A CORYNEBACTERIA RESISTANT TO ASPARTIC ACID ANALOGS AND SULFA DRUGS KYOWA HAKKO KOGYO CO., LTD. (JP) 1979-10-02 US claimed
US-4122158-A FOR TREATMENT OF BURNS; BIODEGRADABLE HYDROPHOBIC POLYMER; SUSTAINED RELEASE ALZA CORPORATION (US) 1978-10-24 US claimed
US-4094976-A ANTICOCCIDIAL CYCLICAMINO ETHANOLS AND ESTERS THEREOF MERCK & CO., INC. (US) 1978-06-13 US claimed
US-4044119-A RUMINANTS, NATIVE MILK SOLIDS, DRUG ENTRAPMENT CUTTER LABORATORIES, INC. (US) 1977-08-23 US claimed
US-4041160-A N-METHYL-2-PYRROLIDONE, ANTICOCCIDIAL AGENTS ABIC LTD. (IL) 1977-08-09 US claimed
US-3983209-A HYDROPHOBIC BIOERODIBLE POLYMER, MICROBIOCIDE OR PROTEOLYTIC ENZYME ALZA CORPORATION (US) 1976-09-28 US claimed