Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382944 | 0.85 | RAB9A (0.36) | L3MBTL1ELOVL1POLBMAPK1AURKA | |
| SCHEMBL9388160 | 0.83 | KDM4E (0.36) | ELOVL1SCN9AALDH1A1 | |
| SCHEMBL9388115 | 0.81 | AURKA (0.42) | SCN9APOLBMAPK1AURKARPS6KB1 | |
| SCHEMBL9304608 | 0.81 | LIPE (0.43) | SCN9AMAPK1NPSR1MAPTLMNA | |
| SCHEMBL9469206 | 0.77 | AURKA (0.42) | L3MBTL1SCN9APOLBAURKARPS6KB1 | |
| SCHEMBL8547515 | 0.77 | AURKA (0.46) | AURKARPS6KB1AURKB | |
| SCHEMBL8548684 | 0.77 | RAB9A (0.42) | L3MBTL1POLBMAPK1AURKARPS6KB1 | |
| SCHEMBL9389676 | 0.77 | AURKA (0.41) | AURKARPS6KB1AURKBEPHX2 | |
| SCHEMBL8544014 | 0.77 | ELOVL1 (0.39) | L3MBTL1ELOVL1POLBMAPK1AURKA | |
| SCHEMBL8548181 | 0.77 | TRPA1 (0.43) | L3MBTL1ELOVL1POLBAURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994004527-A1 | PYRIDYLETHOXY-, PYRIDYLETHYLAMINO-, AND PYRIDYLPROPYL-DERIVATIVES OF QUINOLINE AND QUINAZOLINE AS INSECTICIDES AND FUNGICIDES | DOWELANCO (US) | 1994-03-03 | — | — | WO | claimed |