Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SOD1 | P00441 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428879 | 0.83 | HTR1A (0.49) | HRH1HTR1AALDH1A1MEN1KMT2A | |
| SCHEMBL9383794 | 0.81 | SIGMAR1 (0.55) | HRH1HTR1AALDH1A1MEN1KMT2A | |
| Oxalic Acid SCHEMBL9383037 | 0.81 | SIGMAR1 (0.53) | HRH1HTR1AALDH1A1SMN1; SMN2MEN1 | |
| Oxalic Acid SCHEMBL9383042 | 0.81 | SIGMAR1 (0.53) | HRH1HTR1AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL9388604 | 0.81 | KMT2A (0.60) | HRH1HTR1AALDH1A1MAPTMEN1 | |
| SCHEMBL9429398 | 0.80 | HTR1A (0.56) | HRH1HTR1AALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL8098857 | 0.80 | HTT (0.54) | HTR1AALDH1A1MEN1KMT2ASOD1 | |
| Hydrochloric Acid SCHEMBL9428830 | 0.79 | ALDH1A1 (0.56) | HRH1HTR1AALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11464921 | 0.79 | HTR1A (0.62) | HTR1AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7467094 | 0.78 | KMT2A (0.54) | HTR1AALDH1A1MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |