Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | HRH1 | P35367 | 11/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429398 | 0.83 | HTR1A (0.56) | HTR1AHRH1ALDH1A1KMT2A | |
| SCHEMBL9388133 | 0.83 | HRH1 (0.44) | HTR1AHRH1MEN1ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL9428830 | 0.82 | ALDH1A1 (0.56) | HTR1AHRH1ALDH1A1KMT2A | |
| SCHEMBL9429593 | 0.81 | SOD1 (0.57) | HTR1AHRH1MEN1ALDH1A1KMT2A | |
| SCHEMBL9428613 | 0.79 | HTR1A (0.49) | HTR1AHRH1MEN1KMT2AADRA1D | |
| Hydrochloric Acid SCHEMBL8099007 | 0.78 | USP2 (0.55) | HTR1AALDH1A1KMT2ASIGMAR1DRD2 | |
| SCHEMBL9429034 | 0.77 | MEN1 (0.54) | HRH1MEN1ALDH1A1KMT2AADRA1D | |
| SCHEMBL9429506 | 0.76 | HRH1 (0.44) | HTR1AHRH1ADRA1DADRA1AADRA1B | |
| SCHEMBL9428857 | 0.76 | HRH1 (0.48) | HRH1MEN1ALDH1A1KMT2AADRA1D | |
| SCHEMBL9428708 | 0.76 | HRH1 (0.46) | HRH1MEN1ALDH1A1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0454498-A2 | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-30 | — | — | EP | disclosed |