Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.45 |
| ▸ | CCR5 | P51681 | 12/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391026 | 0.84 | OPRK1 (0.46) | RORCCCR5 | |
| SCHEMBL8670577 | 0.83 | CCR5 (0.54) | CCR5KCNH2 | |
| SCHEMBL8922022 | 0.83 | CCR5 (0.54) | CCR5KCNH2 | |
| SCHEMBL9389652 | 0.77 | OPRK1 (0.56) | — | |
| SCHEMBL9389649 | 0.72 | RORC (0.44) | RORCCCR5 | |
| SCHEMBL9390756 | 0.71 | RORC (0.35) | RORCCCR5 | |
| SCHEMBL16333041 | 0.69 | OPRM1 (0.48) | — | |
| SCHEMBL8699611 | 0.68 | TACR1 (0.55) | CCR5KCNH2 | |
| SCHEMBL5629401 | 0.68 | OPRK1 (0.78) | — | |
| SCHEMBL7955677 | 0.67 | OPRK1 (0.45) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018165-A1 | SULFONAMIDE COMPOUNDS AS OPIOID K-RECEPTOR AGONISTS | PFIZER INC. (US) | 1994-08-18 | — | — | WO | disclosed |