Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392372 | 0.85 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1RAB9ANPC1NPSR1 | |
| SCHEMBL12310822 | 0.74 | L3MBTL1 (0.57) | ALDH1A1L3MBTL1RAB9ANPC1NPSR1 | |
| SCHEMBL11992012 | 0.73 | L3MBTL1 (0.59) | ALDH1A1L3MBTL1RAB9ANPC1NPSR1 | |
| SCHEMBL17980699 | 0.72 | L3MBTL1 (0.54) | ALDH1A1L3MBTL1RAB9ANPC1NPSR1 | |
| SCHEMBL9390224 | 0.72 | RAB9A (0.46) | ALDH1A1L3MBTL1RAB9ANPC1NPSR1 | |
| SCHEMBL18885189 | 0.72 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1RAB9ANPC1NPSR1 | |
| SCHEMBL2270851 | 0.71 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1RAB9ANPC1LMNA | |
| SCHEMBL21847327 | 0.71 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1RAB9ANPC1NPSR1 | |
| SCHEMBL4303760 | 0.71 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1RAB9ANPC1NPSR1 | |
| SCHEMBL29048377 | 0.70 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1RAB9ANPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026715-A1 | AMIDINE DERIVATIVES AS GASTRIC ACID SECRETION INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 1994-11-24 | — | — | WO | disclosed |