Mitoquidone

Mitoquidone

SCHEMBL93910

O=C1c2ccccc2C(=O)c2c1cn1c2Cc2ccccc2C1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 5/20 0.43
▸ MAPT P10636 7/20 0.40
▸ KMT2A Q03164 5/20 0.40
▸ EGFR P00533 2/20 0.40
▸ MAPK1 P28482 2/20 0.40
▸ LMNA P02545 1/20 0.40
▸ L3MBTL1 Q9Y468 3/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ RAF1 P04049 1/20 0.40
▸ ALOX12 P18054 1/20 0.40
▸ MAP2K1 Q02750 1/20 0.40
▸ MEN1 O00255 3/20 0.38
▸ CDC25B P30305 1/20 0.38
▸ TDP1 Q9NUW8 2/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ CES1 P23141 2/20 0.37
▸ BCHE P06276 1/20 0.37
▸ ALOX15 P16050 1/20 0.35
▸ TAAR1 Q96RJ0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mitoquidone SCHEMBL21570575 0.92 MAPT (0.38) MAOAMAPTKMT2AEGFRMAPK1
SCHEMBL10376448 0.86 MAOA (0.50) MAOAMAPTKMT2AMAPK1LMNA
SCHEMBL10376475 0.85 MAPT (0.45) MAOAMAPTKMT2AEGFRMAPK1
SCHEMBL10376512 0.85 ALDH1A1 (0.51) MAOAMAPTKMT2AMAPK1LMNA
SCHEMBL10376125 0.83 MAPT (0.46) MAPTKMT2AEGFRMAPK1LMNA
SCHEMBL10376490 0.82 ACHE (0.32) MAOACES1BCHECYP1A2
SCHEMBL10376478 0.73 MAPT (0.39) MAOAMAPTKMT2AEGFRMAPK1
SCHEMBL10378104 0.71 MAOA (0.38) MAOAMAPTKMT2AEGFRMAPK1
SCHEMBL10376481 0.71 ALOX15 (0.48) MAOAMAPTKMT2AEGFRMAPK1
SCHEMBL10378389 0.69 ALDH1A1 (0.38) MAOAMAPTKMT2AMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 — — US claimed
JP-2011528275-A — — 2011-11-17 — — JP claimed
EP-2313122-A1 DRUG DELIVERY MEDICAL DEVICE Micell Technologies, Inc. (US) 2011-04-27 — — EP claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 — — US claimed
WO-2010009335-A1 DRUG DELIVERY MEDICAL DEVICE MICELL TECHNOLOGIES, INC. (US) 2010-01-21 — — WO claimed
US-20090054369-A1 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS, INC. (US) 2009-02-26 — — US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 — — CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 — — EP claimed
EP-1919929-A4 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND PHARMACEUTICALS INC (US) 2008-08-06 — — EP claimed
EP-1919929-A2 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS RND Pharmaceuticals, Inc. (US) 2008-05-14 — — EP claimed
CN-1846670-A Anticancer implant JINAN SHUAIHUA MEDICINE SCI TE (CN) 2006-10-18 — — CN claimed
CN-1846689-A Slow-released anticancer prepn containing taxane and its synergist JINAN KANGQUAN MEDICINE SCI TE (CN) 2006-10-18 — — CN claimed
CN-1839843-A Fluorouracil slow release injection JINAN SHUAIHUA MEDICINE TECHNO (CN) 2006-10-04 — — CN claimed
CN-1824314-A Slow-release agent containing hormone anticancer medicine JINAN KANGQUAN MEDICINE SCI & (CN) 2006-08-30 — — CN claimed
CN-1748671-A Slow releasing injection containing anti-mitosis medicine KONG QINGZHONG (CN) 2006-03-22 — — CN claimed
CN-1733301-A Anticancer implantation agent KONG QINGZHONG (CN) 2006-02-15 — — CN claimed
CN-1679950-A Anticarcinogenic internal implant agent LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 — — CN claimed
CN-1660436-A Anticancer combination of medication LANJIN BIOLOG ENGINEERING CO L (CN) 2005-08-31 — — CN claimed
EP-0393575-B1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent SEARLE & CO (US) 1994-03-16 — — EP claimed
EP-0393575-A1 Neoplasia treatment compositions containing antineoplastic agent and side-effect reducing protective agent G.D. Searle & Co. (US) 1990-10-24 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054369-A1 PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS SI, SLC29A2, SLC29A1 MAOA 2229/4885MAPT 2400/4885KMT2A 2193/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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