Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938963 | 0.83 | NPC1 (0.42) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL207905 | 0.75 | PIK3CG (0.44) | KDM4EMAPTHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL209566 | 0.75 | KDM4E (0.34) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4150810 | 0.75 | KDM4E (0.42) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL207175 | 0.75 | BACE1 (0.34) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL11784333 | 0.75 | SCN10A (0.36) | MAPTHSD17B10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL533256 | 0.75 | ALDH1A1 (0.43) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL11227035 | 0.74 | NQO2 (0.33) | KDM4EMAPTNPC1RAB9ANQO2 | |
| SCHEMBL407918 | 0.71 | PKM (0.41) | KDM4EMEN1KMT2APKMBACE1 | |
| SCHEMBL208752 | 0.71 | MAP3K14 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | claimed |
| WO-2021216812-A1 | GALACTOKINASE INHIBITORS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-10-28 | — | — | WO | claimed |
| US-10471061-B2 | Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2019-11-12 | — | — | US | claimed |
| US-20190030031-A1 | GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS | THE US OF AMERICA AS REPRESENTED BY THE SEC DEP OF HEALTH AND HUMAN SERVICES (US) | 2019-01-31 | — | — | US | claimed |
| US-20170035760-A1 | GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS | THE US OF AMERICA AS REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN SERVICES (US) | 2017-02-09 | — | — | US | claimed |
| US-20140288100-A1 | GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2014-09-25 | — | — | US | claimed |
| WO-2013043192-A1 | GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-03-28 | — | — | WO | claimed |
| EP-0093252-B1 | THIOMETHYLPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | LUDWIG HEUMANN & CO GMBH (DE) | 1988-03-09 | — | — | EP | claimed |
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH | 2023-05-25 | — | — | US | disclosed |
| CN-108368064-B | 1,2, 3-triazole derivative and insecticide and acaricide comprising the same as active ingredient | 北兴化学工业株式会社 | 2022-04-26 | — | — | CN | disclosed |
| WO-2021216812-A1 | GALACTOKINASE INHIBITORS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-10-28 | — | — | WO | disclosed |
| US-11046659-B2 | 1,2,3-triazole derivative and insecticide and acaricide containing said derivative as active ingredient | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2021-06-29 | — | — | US | disclosed |
| US-10471061-B2 | Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2019-11-12 | — | — | US | disclosed |
| US-20190322630-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-10-24 | — | — | US | disclosed |
| WO-2007034251-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIGANDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |
| WO-2007034253-A1 | AMINO-ALKYL-AMIDE DERIVATIVES AS CCR3 RECEPTOR LIGANDS | SANOFI-AVENTIS (FR) | 2007-03-29 | — | — | WO | disclosed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | disclosed |
| EP-1405853-A1 | ISOXAZOLINE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-0093252-B1 | THIOMETHYLPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | LUDWIG HEUMANN & CO GMBH (DE) | 1988-03-09 | — | — | EP | disclosed |
| US-4701399-A | Photosensitive composition with 2-halomethyl-5-substituted-1,3,4-oxadiazole | FUJI PHOTO FILM CO., LTD. (JP) | 1987-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190030031-A1 | GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS | GALK1, GALC, GCK | KDM4E 3764/4885MAPT 1583/4885HSD17B10 833/4885 |
| US-20140288100-A1 | GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS | GALK1, GALC, B4GALT1 | KDM4E 3836/4885MAPT 1680/4885HSD17B10 783/4885 |
| US-20170035760-A1 | GALACTOKINASE INHIBITORS FOR THE TREATMENT AND PREVENTION OF ASSOCIATED DISEASES AND DISORDERS | GALK1, GALC, B4GALT1 | KDM4E 3757/4885MAPT 1662/4885HSD17B10 786/4885 |
| US-20230158025-A1 | GALACTOKINASE INHIBITORS | GALK1, GCK, GCKR | KDM4E 2218/4885MAPT 2129/4885HSD17B10 2143/4885 |
| US-11046659-B2 | 1,2,3-triazole derivative and insecticide and acaricide containing said derivative as active ingredient | AADAC, CYP51A1, NAT1 | KDM4E 1111/4885MAPT 2506/4885HSD17B10 458/4885 |
| US-10471061-B2 | Galactokinase inhibitors for the treatment and prevention of associated diseases and disorders | GALK1, GALC, GCK | KDM4E 3764/4885MAPT 1583/4885HSD17B10 833/4885 |
| US-20190322630-A1 | 1,2,3-TRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | AADAC, CYP51A1, NAT1 | KDM4E 1111/4885MAPT 2506/4885HSD17B10 458/4885 |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | DDT, CYP1B1, CYP51A1 | KDM4E 1266/4885MAPT 4135/4885HSD17B10 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.