Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538194 | 0.78 | KEAP1 (0.35) | HDAC8KEAP1CYP2C9 | |
| SCHEMBL29752544 | 0.74 | KEAP1 (0.33) | HDAC8KEAP1 | |
| SCHEMBL6167204 | 0.73 | CA12 (0.38) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL19126026 | 0.72 | HSP90AA1 (0.41) | — | |
| SCHEMBL28641198 | 0.71 | GABRA1 (0.40) | KEAP1 | |
| SCHEMBL27360402 | 0.71 | CYP2C9 (0.36) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL17866559 | 0.68 | AHR (0.34) | — | |
| SCHEMBL8861704 | 0.68 | ENPP2 (0.35) | — | |
| SCHEMBL13650780 | 0.68 | ALDH1A1 (0.37) | — | |
| SCHEMBL6139748 | 0.68 | MEN1 (0.36) | HDAC8CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994019515-A1 | GLASSY CARBON CONTAINING METAL PARTICLES | THE OHIO STATE UNIVERSITY (US) | 1994-09-01 | — | — | WO | disclosed |