Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940270 | 0.85 | AKR1B1 (0.38) | AKR1B1CA2CXCL8NAPRTPTGS2 | |
| SCHEMBL38666455 | 0.81 | GABRP (0.45) | AKR1B1NAPRTKDM4ECYP1A2MAPT | |
| SCHEMBL15776163 | 0.75 | RECQL (0.42) | KDM4EMAPT | |
| SCHEMBL29411262 | 0.75 | RECQL (0.42) | KDM4EMAPT | |
| SCHEMBL13990810 | 0.75 | GRIN2D (0.39) | PTGS2KDM4EMAPTL3MBTL1TDP1 | |
| SCHEMBL4837065 | 0.73 | AKR1B1 (0.45) | FABP4FABP5AKR1B1CA2CXCL8 | |
| SCHEMBL3738359 | 0.72 | ABCB11 (0.41) | FABP4FABP5AKR1B1CA2CXCL8 | |
| SCHEMBL29718785 | 0.72 | ABCB11 (0.41) | FABP4FABP5AKR1B1CA2CXCL8 | |
| SCHEMBL4478290 | 0.72 | L3MBTL1 (0.47) | CYP1A2MAPTLMNAL3MBTL1CYP2C9 | |
| SCHEMBL15776032 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254416-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2016-09-07 | — | — | EP | disclosed |
| US-8653078-B2 | Herbicidal pyrido[2,3-b]pyrazines | SYNGENTA LIMITED | 2014-02-18 | — | — | US | disclosed |
| US-20130137574-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2013-05-30 | — | — | US | disclosed |
| US-8338598-B2 | Herbicidal pyrido[2,3-B]pyrazines and their use as herbicides | SYNGENTA LIMITED | 2012-12-25 | — | — | US | disclosed |
| US-20110021351-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2254416-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009090402-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137574-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, CBR1 | FABP4 4493/4885FABP5 3707/4885AKR1B1 58/4885 |
| US-20110021351-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, TH | FABP4 4690/4885FABP5 4333/4885AKR1B1 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.