Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198824 | 0.87 | PKM (0.51) | MAPK1PKMHTR1AUSP2MEN1 | |
| SCHEMBL9398442 | 0.85 | P2RX7 (0.48) | MAPK1PKMHTR1AUSP2MEN1 | |
| SCHEMBL9398311 | 0.85 | LMNA (0.60) | MAPK1PKMHTR1AUSP2MEN1 | |
| SCHEMBL9397264 | 0.84 | MAPK1 (0.54) | MAPK1PKMHTR1AUSP2MEN1 | |
| Hydrochloric Acid SCHEMBL9397163 | 0.83 | MAPK1 (0.47) | MAPK1PKMHTR1AUSP2MEN1 | |
| SCHEMBL9397246 | 0.83 | PKM (0.53) | MAPK1PKMHTR1AUSP2MEN1 | |
| SCHEMBL2456938 | 0.81 | MAPK1 (0.51) | MAPK1PKMHTR1AUSP2MEN1 | |
| SCHEMBL9397286 | 0.81 | LMNA (0.63) | MAPK1PKMHTR1AUSP2MEN1 | |
| SCHEMBL9398291 | 0.73 | MAPT (0.43) | MEN1DRD2DRD3KMT2AALDH1A1 | |
| SCHEMBL9397299 | 0.73 | CYP3A4 (0.56) | MAPK1HTR1AMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |