Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 4/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.49 |
| ▸ | HTR3B | O95264 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198833 | 0.86 | PKM (0.53) | MAPK1PKMHTR1ALMNAALOX15 | |
| SCHEMBL9398450 | 0.84 | P2RX7 (0.55) | MAPK1PKMLMNAALOX15TSHR | |
| SCHEMBL9397253 | 0.84 | MAPK1 (0.51) | MAPK1PKMHTR1AHTR3EHTR3B | |
| SCHEMBL9398318 | 0.83 | LMNA (0.62) | MAPK1PKMLMNATSHRMEN1 | |
| Hydrochloric Acid SCHEMBL9397166 | 0.83 | MAPK1 (0.49) | MAPK1PKMHTR1ALMNAALOX15 | |
| SCHEMBL9397256 | 0.83 | PKM (0.56) | MAPK1PKMHTR1ALMNATSHR | |
| SCHEMBL2456939 | 0.81 | CA12 (0.54) | MAPK1PKMLMNAMEN1CYP3A4 | |
| SCHEMBL9397291 | 0.80 | LMNA (0.65) | MAPK1PKMLMNATSHRMEN1 | |
| SCHEMBL9196105 | 0.80 | LMNA (0.60) | MAPK1LMNATSHRL3MBTL1ALDH1A1 | |
| SCHEMBL9397301 | 0.75 | TSHR (0.57) | HTR1ALMNAALOX15TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |