Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9397252 | 0.96 | FTO (0.40) | FTOCYP3A4TSHRNFKB1THPO | |
| SCHEMBL9349852 | 0.85 | FTO (0.41) | FTOMAPTLMNACOMTKDM4E | |
| SCHEMBL9398247 | 0.84 | ALDH1A1 (0.54) | CYP3A4MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL9344868 | 0.84 | MAPT (0.41) | FTOTSHRMAPTLMNACOMT | |
| SCHEMBL9398477 | 0.82 | SMN1; SMN2 (0.46) | FTOCYP3A4MAPTLMNAKDM4E | |
| SCHEMBL9345574 | 0.81 | FTO (0.40) | FTOMAPTLMNACOMTKDM4E | |
| SCHEMBL9398291 | 0.79 | MAPT (0.43) | FTOMAPTLMNAKDM4ESLC40A1 | |
| SCHEMBL9349805 | 0.79 | SMN1; SMN2 (0.41) | MAPTLMNAKDM4EALDH1A1HTR6 | |
| SCHEMBL9397274 | 0.78 | CYP3A4 (0.64) | CYP3A4TSHRNFKB1THPOHIF1A | |
| SCHEMBL9397299 | 0.78 | CYP3A4 (0.56) | CYP3A4TSHRNFKB1THPOHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |