Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | DDX3X | O00571 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466759 | 0.91 | GRIK1 (0.60) | ALDH1A1KMT2AMEN1GRIK1DDX3X | |
| SCHEMBL9400341 | 0.89 | ALDH1A1 (0.70) | BAZ1AALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL19880777 | 0.85 | TP53 (0.65) | ALDH1A1KMT2AMEN1GRIK1CNR1 | |
| SCHEMBL7098404 | 0.83 | TP53 (0.68) | BAZ1AALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL3100071 | 0.80 | GRIK1 (0.51) | ALDH1A1KMT2AMEN1GRIK1DDX3X | |
| SCHEMBL30589624 | 0.79 | MEN1 (0.82) | ALDH1A1KMT2AMEN1TRPV1GRIK1 | |
| SCHEMBL28914350 | 0.79 | MEN1 (0.82) | ALDH1A1KMT2AMEN1TRPV1GRIK1 | |
| SCHEMBL7097165 | 0.78 | ALDH1A1 (0.67) | BAZ1AALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL22025929 | 0.78 | ALDH1A1 (0.61) | BAZ1AALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL31078919 | 0.77 | BAZ1A (0.69) | BAZ1AALDH1A1CYP1A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249630-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2007-10-25 | — | — | US | disclosed |
| US-20050209338-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209338-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | PHOSPHO1, PNMT, PEBP1 | BAZ1A 1167/4885ALDH1A1 2157/4885CYP1A2 226/4885 |
| US-20070249630-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | PHOSPHO1, PNMT, PEBP1 | BAZ1A 1167/4885ALDH1A1 2157/4885CYP1A2 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.