Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | FABP1 | P07148 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL7760670 | 0.95 | HSD17B10 (0.35) | ALDH1A1HDAC6HDAC1HTTCYP1A2 | |
| Diethylamine SCHEMBL7762446 | 0.88 | KMT2A (0.34) | KMT2AHDAC6HDAC1RAB9AELANE | |
| Diethylamine SCHEMBL7759271 | 0.88 | GABRA2 (0.35) | ALDH1A1KMT2AHDAC6HDAC1RAB9A | |
| SCHEMBL7759279 | 0.87 | GHSR (0.40) | ALDH1A1KMT2AHDAC6HDAC1HTT | |
| Diethylamine SCHEMBL7762459 | 0.87 | MEN1 (0.36) | ALDH1A1KMT2AHTTRAB9AL3MBTL1 | |
| Diethylamine SCHEMBL7756020 | 0.86 | L3MBTL1 (0.39) | ALDH1A1KMT2AHDAC6HDAC1HTT | |
| Diethylamine SCHEMBL8973476 | 0.86 | MEN1 (0.35) | ALDH1A1KMT2ARAB9AL3MBTL1MAPT | |
| Diethylamine SCHEMBL7760658 | 0.86 | HSD17B10 (0.40) | ALDH1A1KMT2AHDAC6HTTRAB9A | |
| SCHEMBL7760668 | 0.82 | CNR2 (0.41) | ALDH1A1KMT2ARAB9AL3MBTL1MAPT | |
| Diethylamine SCHEMBL9400404 | 0.81 | POLB (0.37) | ALDH1A1KMT2AHTTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665462-B1 | Thermofixable photosensitive recording material and process for preparing thereof | NEW OJI PAPER CO LTD (JP) | 2001-04-18 | — | — | EP | disclosed |
| US-5565306-A | SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN | NEW OJI PAPER CO., LTD. (JP) | 1996-10-15 | — | — | US | disclosed |
| EP-0665462-A1 | Thermofixable photosensitive recording material and process for preparing thereof | NEW OJI PAPER CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |