Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401133 | 0.91 | KMT2A (0.43) | MTNR1AMTNR1BKMT2ACYP1A2CYP3A4 | |
| SCHEMBL9401142 | 0.88 | KMT2A (0.49) | MTNR1AMTNR1BKMT2ACYP1A2CYP3A4 | |
| SCHEMBL9401169 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BKMT2ACYP1A2CYP3A4 | |
| SCHEMBL9401148 | 0.83 | KMT2A (0.40) | MTNR1AKMT2AHPGDTDP1MEN1 | |
| SCHEMBL6768454 | 0.76 | MTNR1A (0.59) | MTNR1AMTNR1BKMT2ACYP1A2CYP3A4 | |
| SCHEMBL5510275 | 0.71 | KDM4E (0.56) | MTNR1AMTNR1BKMT2ACYP1A2CYP3A4 | |
| SCHEMBL4066208 | 0.71 | ALDH1A1 (0.58) | ALDH1A1 | |
| SCHEMBL18919603 | 0.69 | TSHR (0.58) | MTNR1AMTNR1BKMT2ACYP1A2CYP3A4 | |
| SCHEMBL7497957 | 0.69 | KMT2A (0.51) | MTNR1AMTNR1BKMT2ACYP1A2CYP3A4 | |
| SCHEMBL2087168 | 0.69 | HPGD (0.61) | MTNR1AMTNR1BKMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314908-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1994-05-24 | — | — | US | disclosed |