Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | FPR1 | P21462 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401130 | 0.88 | MTNR1A (0.51) | KMT2AALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL9401133 | 0.87 | KMT2A (0.43) | KMT2AALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL9401169 | 0.87 | MTNR1A (0.58) | KMT2AALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL9401148 | 0.77 | KMT2A (0.40) | KMT2AALDH1A1MTNR1AMEN1KDM4E | |
| SCHEMBL7692306 | 0.74 | KDM4E (0.56) | KMT2AALDH1A1METMTNR1AMTNR1B | |
| SCHEMBL9401139 | 0.73 | ALDH1A1 (0.54) | KMT2AALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL9751553 | 0.72 | MTNR1A (0.79) | KMT2AALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL11493601 | 0.71 | MAPT (0.52) | KMT2AALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL9401128 | 0.70 | MTNR1A (0.64) | KMT2AALDH1A1MTNR1AMTNR1BMEN1 | |
| SCHEMBL9401123 | 0.70 | KDM4E (0.44) | KMT2AALDH1A1METMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314908-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0549916-A2 | Compounds useful as antiproliferative agents | WHITBY RESEARCH, Inc. (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5206377-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1993-04-27 | — | — | US | disclosed |