Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401130 | 0.83 | MTNR1A (0.51) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL9401133 | 0.80 | KMT2A (0.43) | KMT2AMEN1ALDH1A1KDM4EUSP2 | |
| SCHEMBL9401142 | 0.77 | KMT2A (0.49) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL9401143 | 0.71 | KDM4E (0.53) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL9302872 | 0.71 | MTNR1A (0.71) | KMT2AMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL9298691 | 0.69 | AHR (0.66) | ALDH1A1P2RX3 | |
| SCHEMBL3255855 | 0.69 | SIGMAR1 (0.62) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL9401169 | 0.68 | MTNR1A (0.58) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL7321937 | 0.66 | MEN1 (0.49) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL11703717 | 0.65 | KDM4E (0.50) | KMT2AMEN1ALDH1A1KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314908-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0549916-A2 | Compounds useful as antiproliferative agents | WHITBY RESEARCH, Inc. (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5206377-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1993-04-27 | — | — | US | disclosed |