SCHEMBL9401286

SCHEMBL9401286

COc1cc(OC)nc(SC(CO)Cc2ccc(Cl)cc2)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SLC6A2 P23975 1/20 0.34
SLC6A3 Q01959 1/20 0.34
MMP1 P03956 1/20 0.34
CYP3A4 P08684 1/20 0.34
ADORA3 P0DMS8 2/20 0.34
ADORA1 P30542 1/20 0.34
ALOX5 P09917 2/20 0.34
ATM Q13315 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9401523 0.88 ALOX5 (0.43) CYP1A2CYP2C19CYP2D6L3MBTL1ALOX5
SCHEMBL9401367 0.86 PTGES (0.43) ALOX5
SCHEMBL9401551 0.85 COPS5 (0.35) CYP1A2CYP2C9CYP2C19CYP2D6CYP3A4
SCHEMBL9401349 0.81 KCNJ5 (0.37) MAPTL3MBTL1NPSR1POLB
SCHEMBL9401526 0.78 ALDH1A1 (0.39) CYP1A2ADORA3ADORA1ALOX5
SCHEMBL9401522 0.78 EDNRB (0.36) EDNRBEDNRAKMT2AMEN1CYP1A2
SCHEMBL9401293 0.77 ALDH1A1 (0.36) L3MBTL1ALOX5
SCHEMBL9401566 0.76 CTSA (0.35) ALOX5
SCHEMBL9401275 0.76 ALDH1A1 (0.35) CYP1A2ADORA3ADORA1ALOX5
SCHEMBL9401295 0.75 CTSA (0.37) L3MBTL1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5346880-A Pre- and postemergence NIHON BAYER AGROCHEM K.K. (JP) 1994-09-13 US disclosed
EP-0565951-A1 Herbicidally active pyrimidinylthioalkane derivatives NIHON BAYER AGROCHEM K.K. (JP) 1993-10-20 EP disclosed