Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942027 | 0.75 | MAOA (0.44) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL860951 | 0.72 | GRM2 (0.43) | MAOAMAOBKDM4EKMT2A | |
| SCHEMBL455949 | 0.69 | MAOA (1.00) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL29389300 | 0.68 | MAOA (0.56) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL92707 | 0.68 | MAOA (0.56) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL28400797 | 0.67 | MAOA (0.95) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL15131691 | 0.65 | MAOA (0.73) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL516091 | 0.65 | TDP1 (0.59) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL4058577 | 0.65 | MAOA (0.52) | MAOAMAOBKDM4EALDH1A1TDP1 | |
| SCHEMBL1620592 | 0.65 | DCPS (0.63) | MAOAMAOBKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254416-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2016-09-07 | — | — | EP | disclosed |
| US-8653078-B2 | Herbicidal pyrido[2,3-b]pyrazines | SYNGENTA LIMITED | 2014-02-18 | — | — | US | disclosed |
| US-20130137574-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2013-05-30 | — | — | US | disclosed |
| US-8338598-B2 | Herbicidal pyrido[2,3-B]pyrazines and their use as herbicides | SYNGENTA LIMITED | 2012-12-25 | — | — | US | disclosed |
| US-20110021351-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-27 | — | — | US | disclosed |
| EP-2254416-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009090402-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137574-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, CBR1 | MAOA 379/4885MAOB 223/4885KDM4E 2101/4885 |
| US-20110021351-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, TH | MAOA 158/4885MAOB 101/4885KDM4E 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.